Neuroleptic Malignant Syndrome에 합병되 어 나타난 급성 신부전증 1예

Acute Renal Failure, a Sequela o f the Neuroleptic Malignant Syndrome

Neuroleptic malignant syndrome(NMS) is an uncommon but fatal idiosyncratic reaction to neuroleptics. It comprises fever, muscular rigidity, altered consciousness and autonomic dysfunction. The most common serious complication of NMS is rhabdomyolysis, which produces acute myoglobinuric renal failure. The authors experienced a schizophrenic male patient with acute renal failure as a sequela of NMS. The patient was 27-year-old man who had received haloperidol for 9 years. Emergency hemodialysis, hydration and diuretics promoted recovery of impaired renal function. The patient survived the acute episode of NMS without any sequela and resumed his treatment with neuroleptics.