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Factors Influencing Drug Noncompliance in Schizophrenic Patients

The authors investigated the factors influencing drug noncompliance in schizophrenic patients in Yongin Mental Hospital. 37 of 417 schizophrenic patients taking chlorpromazine proved to be drug noncompliant by Forrest urine test. We selected 22 of them who could give reliable answers to self-report questionaire as a noncompliant group. We also selected 22 patients as a control group who proved to be drug compliant by Forrest urine test. Using self-report questionaire we compared the difference in the knowledge about the medication, attitudes concerning the drug, opinions on the therapist-patient relationship and experiences of the drug side effects between two groups. The results were as follows •• 1) The rates of drug noncompliance of 417 patients taking chlorpromazine were 14.5% at the 1st urine test, 21.9% at the 2nd urine test, respectively. 2) The more the dose of chlorpromazine patient takes, the higher was the drug noncompliant rate. 3) The average frequency of medication per day of the drug compliant group was 2,6times per day, which was less than that (2.9 times per day) of the drug noncompliant group. 4) In comparison with the drug noncompliant group, the patients of the drug compliant group showed a tendency to believe that mental hospital teams other than the doctors were more concerned with them. 5) In comparison with the drug noncompliant group, the patients of the drug compliant group showed a tendency to fed more tension when they faced the mental hospital team. 6) The two groups were not signficantly different in their knowledge about the medication, attitudes concerning the drug, and experiences of the drug side effects.