The author evaluated the relationship betw een fiife changes’ and diabetes mellitus. T h e s e 《life changes’ were experienced d uring the year before the onset of illness. By use of ‘Recent life change Questionaire ; data were collected from informal, personal interview with 73 cases of diabetes mellitus and 113 subjects were used as control Some of the results and conclusions are as follows : 1) In the analysis of mean LC U (‘life change unit’), the subjects of diabetes mellitus (269.1 LCU) have more of life changes’ than did the control group (147 LCU) significant to p 〈0.01. 2) There are no statistically meaningful differences between the LCUs of male and female diabetics. 3) The analysis of categories of ‘life changes , those subjects with diabetes mellitus have more life changes’ in the category of change of marrital life’, ‘change of health，, change of family life， and ‘change of financial life’ than did the control group significant to p(0.01. 4) In conclusion, there are statistically meaningful relationships between “life changes, and the onset of diabetes mellitus. This result supports the hypothesis that the diabetes may be developed by stress.
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