精神分裂病에서 血獎 Cyclic Adenosine 3 ,5 - Monophosphate ( Cyclic AMP)에 關한 硏究

A Study on the Plasma Cyclic Adenosine 3 ,5 - Monophosphate (Cyclic AMP) in Schizophrenia

The authors estimated plasma cyclic AMP in 10 schizophrenic patients who had not received neuroleptic treatment and who had received neuroleptic treatment for 2 weeks, and 6 normal volunteers. 1} Though slightly lower than controls, plasma cyclic AMP in schizophrenics(15.95 士 3*23 pmol/100ml) (mean士standard error) was not significantly different from controls. 2) 2weeks after medication with neuroleptics ,the plasmacyclic AMP in schizophrenics (13.35 土1.16 pmol /100ml) was lower than drug —free groups,but there is no statistical significance. 3) Plasmacyclic AMP in males (20. 00 土6.10pmol/100ml in schizophrenics, 11.17±1.45pmol /100ml in males) were somewhat higher than controls, but there is no statistical significance.