Mianserin에 의한 불안정 하지 증후군 4 례

4 Cases of Mianserin Induced Restless Legs Syndrome

This is a clinical report of 4 cases of restless legs syndrome developed in patients diagnosed as major depressive disorder by DSM — 1 criteria, who were treated with *Mianserin * which is known as one of the new generation tetracyclic anti depressants. With the duration of the average of 1 or 2 weeks following the administration of mianserin, all of these patients showed characteristic symptoms of restless legs syndrome which included unpleasant creeping sensation and vague discomfort on the both legs at rest typically in the evening and during the night For the prevention of exacerbation of these symptoms, hotbag, diazepam, lowering or discontinuation of mianserin, and shifting to another antidepressants including tricyclic anti depressants had concurrently been tried and proved effective