선천성 구순,구개열 환자에 대한 역학적 연구

Epidemiologic Study on Patients With Congenital Cleft Lip and Palate

Cleft lip and palate are most common congenital deformity to affect the orofacial region. Cleft lip and palate are caused by abnormal development of primaiy and secondaiy palate. It s causative mechanism is not completely understood, but genetic and envirorunental factors play an important role. Many epidemiologic surveys have been done extensively about incidence, racial influence, sex ratio, parent age, associated syndrome, and genetic factors. These researches are useful to dissolve many problems in prevention and treatment of cleft lip and palate. We performed epidemiologic survey of cleft lip and palate who visited the department of Oral & Maxillofacial surgery, Guro Hospital of Korea University from 1995 to 2001.