電氣衝擊이 白鼠의 線條體内 도파민 受容體에 미치는 影響

Effect of Electroconvulsive Shock (ECS) on Dopamine Receptors in the Rat Corpus Striatum

For the purpose of examining the nature of certain psychiatric illnesses on which ECS has some beneficial effect authors observed the effect of ECS on striatal dopamine receptors of male albino Sprague-Dawley rats,: divided into twelve groups according to three factors-treatment (ECS， sham-ECS and control), frequency (one time and seven times) and maturity (interval between decapitation and the last treatment). The result is： there was no significant difference between groups. Through the finding .of Jip difference between sham-ECS and control groups we can exclued the possible relationship of nonspecific stress effects induced by sham-ECS with the ECS-induced effect The finding that there was nd significant difference between ECS and control groups was discussed carefully in view of inappropriateness of experimental model. Further well-controlled researches are needed to examine the delayed effect of ECS.