Changes on EEG after bilateral and unilateral ECT was studied in 12 young adult schizophrenic patients who were adm itted st Seoul Municipal Mental Hospital. Their EEG data were obtained during the interictal period of serial ECT sessions and subjected to global quantitative analysis by visual assessment. Some significant findings are summarizcol as follows: Repeated ECT resulted in increased EEG slow wave activity more see in the frontal and temporal leads which became gradually generalized in forms of occasional burst and run. No spike and focalized activities were seen. The degree of slowing and its am plitude was directly related to the f number of ECT sessions. As the successive four to six treatm ents were administered, the slowing became more persistent and widespreaded with high voltage paroxysmal activities, while the alpha rhythm became disturbed and disappeared. After seven to eight serial treatment, the percent time delta remained constant in plateau or failed off. Fourteen days after the last 10th treatment, 34 percent time of slow wave activities was recorded in frontal lead of bilateral ECT group and 25 percent of unilateral ECT group. Minor lateralized asymmetries of frequancy and amplitude which were predominently right sided, appeared more in the rig h t unilateral ECT group (4 in 6 cases) than the bilateral group (1 in 6 cases). The amount of post-ECT slow wave activity did not revealed m ajor difference between these kinds of ECTs and was closely related to the number of ECT sessions and to the pretreatment EEG with individual variations. No relationship was found between the therape utic response, degree of amnesia or confusion, and EEG findings after electroconvulsive therapy.
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