Lorazepam is a new benzodiazepine derivative with potent anxiolytic and sedative properties inherent in the group. Many studies suggest that it is a more potent drug with minimal side effects. There is a structural similarity between lorazepam and oxazepam, since both result from a demethylation and hydroxylation of diazepam, with lorazepam being distinguished by the presence of a chlorophenyl side chain. It has been reported that chlorpromazine, lithium and several psychotropic drugs elevated the blood alcohol level in rabbits. In view of these findings, the author conducted an animal experiment to investigate the effect of lorazepam on blood alcohol level in rabbits.
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