알콜과다소모자의 이화학적 소견

Laborotory Markers for Chronic Excessive Alcohol Consumers

This article examined the commonly used laboratory markers of excessive alcohol consumers (elevated MCV, GG TP, ASAT and ALAT values) in 94 alcoholic men and 50 psychotic men admitted to Seoul Municipal Mental Hospital. The results were as follows ; 1) The alcoholics(n=94) had significantly higher levels of MCV, GG TP, ASAT and ALAT than the nonalcoholics ( n =50). 2) The alcoholics had significantly higher percentages of the abnorm al elevated values of MCV, GGTP, ASAT and ALAT than the nonalcoholics. 3) GGTP was the most sensitive marker of excessive alcohol consum ption being positive in 81 % of alcoholics. As compared to it MCV, ASAT and ALAT were far less sensitive (42%, 37% and 29% respectively), 4) The sensitivities of laboratory markers of excessive alcohol consum ption were improved by using various com binations of MCV, GGTP, ASAT, and ALAT (range of percentage 85 〜 88%). 5) Age-related differences in laboratory markers were not apparent. Therefore it can be concluded that the laboratory markers are useful in the detection of excessive alcohol consumers and the diagnosis of alcohol-related health problem.