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Authors reported a case of rapid cycling affective disorder (RCAD ) developed after the damage of temporal lobe by traffic accident. Patient showed sharp transients on bilateral temporal area of nasopharyngeal E E G and a significant decrease of blood flow o f left temporal area on SPECT. The kindling desensitization in the trmporal lobe and limbic system has been accepted as the most probable hypothesis in development of RCAD . In our case, same pathophysiology was thought to play a causative role in development of RCAD .
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