Many studies of lithium maintenance treatment for the tnanic-depressive patients Wef6 reported. In order to estimate the effectiveness of lithium maintenance treatment as a prevent inn of recurrence of maic-depressive attacks, the authors selected 12 cases of maic-depressive psychoses who had more than one attack in the past several years and under treatment of lithium maintenance treatment in the Department of Neuropsychiatry, Woo Sok Hospital, Korea University. The result were as follows: 1. Only 4 patients among 11 cases who has no recurrence so far up to the date of this reported showed 0- 6-1.2mEq/L in serum Lithium level. 2. One patient who was under control for about 12 months with 600mg of lithium carbonate had another attack again 10 months after dropping out of the maintenance treatment. 3. There is no evidence of interrelations between body weight of the patients, serum lithium level and maintenance dosage.
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