Priapism is a rare but serious adverse effect of psychotropic medication from their peripheral alpha-adrenergic blocking action, perhaps directly blocking the sympathetic impulse for detumescence. Ont patient with chronic schizophrenia who admitted at urologic department developed this side effect during treatment with oral antipsychotics,thioridazine, haloperidol and antidepressant, trazodone. Awareness of these association and serious consequences of this disorder may be helpful to clinician in choosing psychotropic medication that minimize the risk of developing priapism
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