정신분열증 환자에서 낮병원 치료가 약물 유지치료에 미치는 영향

Effects of Day Hospital Treatment on the Maintenance Psychopharmacotherapy in Schizophrenic Patients

The purpose of this study was to investigate the effects of the day-hospital treatment for the schizophrenic patients through the evaluation o f maintenence drug dosage. In order to do this, subject group were composed of thirty patients with day hospital treatment and psychopharmacotherapy, whereas the controlled group had only psychophamacotherapy. The ratio of drug dosage change were compared betwen these two groups at the time of baseline, after three month, six months, and nine months. Baseline time for subject group was defined as the time when the patients was transferred to day-hospital treatment after hospital discharge. The controlled is the time when the paients started to have only outpatient treatment after hospital discharge. The results were as follows ； 1) For the first three months, the comparing the ratio o f drug dosage change between subject and control groups was significantly decreased(p < 0.005). 2) From three to six months, there were no significant difference of drug dosage between two groups. 3) From six to nine months, subject group was also significantly decreased in drug dosage(p < 0.05). In conclusion, day hospital schizophrenic patients with active psychosocial program are expected to have successful social rehabilitation, because active day hospital program is possible to reduce maintenence dosage without drug-induced side effect