A Case of Schizophreniform Psychosis in a True Hermaphrodite

46,XX True hermaphroditism is a clinical condition in which both ovarian and testicular tissues can be observed in a person. Cases of psychoses in true herm aphrodites have been rarely reported in the w hole world. Recently, we experienced a rare case of psychosis in a 24 year-old female who was bom with ambiguous genitalia and had been confirmed as a true hermaphrodite by chromosomal analysis. This case was reported and related articles were reviewed. The patient was raised as a boy until hermale genitalia was castrated and she was raised as a girl at the beginning of the 3rd grade of her elem entaiy school period. She was adapted well until she failed the teachers’ employment exam ination just after graduation of her college. Clinical features of religious delusions, bizarre behavior, self-harm , incoherent speech, sudden catatonic posturing, mutism , negativism were observed as well as transient cognitive deficit such as disorientation and loss of memory. Physical anom alies such as microcephaly, long extremity bones and ambiguous genitalia in addition to the chromosom al study of 46X~X, + dert(X ; ? ) suggest true herm aphroditism . The case of a psychosis in true hermaphroditism supports the notion that sex chromosomal anom alies may be partly involved in the pathogenesis of schizophrenia