주의력 결핍과잉운동장애 아동의 뇌청각 사건유발전위

Auditory Event Related Potentials in Children with Attention Deficit Hyperactivity Disorder

In the present study, the authors hoped to determine whether the children with Attention Deficit Hyperactivity Disorder differed from normals in Auditory Event Related Potential study. The study was performed by selective attentional tasks. Study subjects were grouped into attention deficit hyperactivity disorder group (N = 9) and normal control group (N = 8) according to clinical information, DSM-III-R diagnostic criteria, several psychological tests. During the selective attentional tasks, subject were submitted to odd-ball test with auditory stimuli of the two different frequencies, under the two conditions of attention or ignorance. Test was performed twice, the first under the condition that should be attend to auditory stimuli and count the target sound, the second condition with reading. The results are as follows : 1) Considering the average value of auditory event related potential wave components over all conditions, the amplitude of wave components at each electrode site was different Amplitude of N2 wave was larger at anterior portion of the brain and the amplitude of P3b was larger at posterior portion of the brain. 2) At Pz electrode site, amplitude of N2 wave to target and non-target sound was different between boys with attention deficit hyperactivity disorder and normal controls. Amplitude of N2 wave in attention deficit hyperactivity disorder was smaller than normal controls. 3) At Fz, Cz, Pz electrode site, amplitude of P3b wave elicited by target sound was larger than by non-target sound. This discrepancy was not interrelated with subjects group factor or attentiation factor. 4) Amplitude of N2 wave at Fz, Cz electrode site was different according to attend condition. Amplitude of N2 wave under the condition attended to auditory stimuli was larger than under the ignore condition. This discrepancy was not interrelated with subject group factor or stimulus factor. 5) Amplitude of P3b wave at Pz was significantly different according to attention. Amplitude of P3b was greater at attend condition. This discrepancy was not influenced by subject group factor or stimulus type factor. In conclusion, some findings of this study were suggestive there are differences in brain auditory event related potential between the two groups (ADHD vs controls). Further study is necessary to prove and conclude it