A nationwide epidemiological study of mental disorders including bipolar disorder and major depression in Korea using DIS-III Korean version was conducted in the Capital City o f Korea (Seoul) and 20 rural areas and the results were compared with those o f 9 other countries. The results were as follows : 1) The lifetime prevalence rate of obsessive-compulsive disorder was 0.42%, 0.40% in seoul and 0.44% in rural areas. The lifetime prevalence rate of major depression was 3.37% (3.31 % in Seoul and 3.47% in rural areas). 2) As for sex, the lifetime prevalence rates or bipolar disorder were 0.65^ in male and 0.20% in female, and those of major depression were 2.61 % in male and 4.06% in female. 3) The most prevalent age group of bipolar disorder was 18〜 24 years old group and was 45〜65 years old group in major depression. 4) The lifetime prevalence rates of bipolar disorder were compared between 10 countries (K orea, USA, Canada, Puerto Rico，France, Germany, Italy, Lebanon, Taiwan, New Zealand). It was lowest in Korea, Germany and Taiwan(0.4%) and highest in New Zealand(1.4%). The earliest mean age of onset was shown in USA, 18.1 yrs. old, and the latest in Puerto Rito, 29.2yrs, old. 5) Also the lifetime prevalence rates of major depression were compared between 10 countries. The lowest was 1.5% in Taiwan, and the highest was 19.0% in Lebanon. The lowest annual prevalence rate was 0.8% in Taiwan and the highest was 6.3% in Germany. The ealiest mean age of onset was 24.8 yrs. old in Cahada and the latest was 34.8 yrs. old in Italy. 6) As for sex, in bipolar disorder, the prevalence rate among the males were lowest in Germany (0.0%) and highest in New Zeafound(l.7%). Those among the females were lowest in Korea(0.2%) and highest in New Zealand(1.2%). 7) In major depression, the prevalence rate among the males were lowest in TaiwanCl.l and highest in Lebanon(l4.7%). Those among the females were lowest in Taiwan(l.8%), and highest in Italy(l8.1%). 8 ) Symptom occuring in 50% or more persons with major depression were as follows: (1) poor appetite—Korea，Canada, Puerto Rico, France, Lebanon, Taiwan. (2) weight loss—Lebanon. (3) insomnia and loss of energy-all countries. (4) retardation, agitation and decreased in sex-Lebanon. (5) worthless, guilt and concentration-all countries (6) slowed thinking-Korea, Canada, Lebanon, Taiwan, New Zealand. (7) thought of death —all countries except Germany, Taiwan. 9) Symptom occuring in 60% or more persons with major depression were as follows (1) poor appetite-Korea, Lebanon, Taiwan. (2) insomnia and loss of energy—all countries. (3) decreased sex—Lebanon. (4) worthless, guilt—all countries except Puerto Rico, Lebanon, Taiwan. (5) concentration—all countries except Korea and Germany. (6) slowed thinking—Korea, Canada, Lebanon, Taiwan. (7) thought of death-USA, Canada, Puerto Rico, Lebanon, New Zealand.
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