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KCI등재 학술저널

알콜금단 증후군의 치료에서 Carbamazepine과 Lorazepam의 효과 비교

Comparative Effect of Carbamazepine and Lorazepam on Treatment of Alcohol Withdrawal Syndrome

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In order to compare the effects of carbamazepine and lorazepam on alcohol withdrawal syndrome, a comparative study of carbamazepine and lorazepman was conducted with 40 cases of aocoh이 withdrawal syndrome during period from March, 1990 to August, 1991. The patients were assigned randonly to either cabamazepine(600mg/day) treated group or lorazepam (6 mg/day) treated group for 8 days. During the trial period, target withdrawal symptoms and side effect were recorded daily. In general, carbamazepine was more efficacious to lorazepam in treating the withdrawal syndrome and not different with respect to side effects. It is concluded that carbamazepine, which is well tolerated and does not produce any addication, might offer a valuable alternative drug in the treatment of alcohol withdrawal symptoms.

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