In order to evaluate the prevalence of abnormal neurologic signs, an extensive neurologic examination was done in 41 schizophrenic patients 28 m ood disorder patients, and 28 normal controls. The patient groups were diagnosed by DSM-III-R, and the neurologic examinations included 79 items of Woods’ standard neurologic examination and 45 items of Merriams, s neurological sign inventory. In the Woods’ standard neurologic examination, the abnormal findings were found in 73.2% of schizophrenic patients, 51.5% of mood disorder patients and 1.4% of normal controls. The schizophrenia group had significantly higher total scores than both the m ood disorder and normal control group ’ and both the schizophrenic and m ood disorder patients had higher total scores than norm al controls. In the MerriarrTs neurologic sign inventory, the schizophrenic patients had significantly more impared performance than both mood disorder patients and normal controls. There were significant correlations between abnormal neurological sign and duration of the illness, number of previous hospitalization, duration of index hospitalization, and dosage of chlorpromazine in schizophrenic patients.
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대상 및 방법
성 적
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