만성 정신분열증 환자에서 Schneider의 일급증상의 예후적 가치에 대한 연구

A Study for Prognostic Values of Schneiderian First-Rank Symptoms in Chronic Schizophrenics

In order to investigate the prognostic values of Schneiderian first-rank symptoms in chronic schizophrenis, the authors divided the subjects, 40 patiens with schizophrenia, into two groups according to the presence or absence of Schneiderian first-rank symptoms. We compared the premorbid and morbid factors, which might be associated with long term outcome between two groups, and also short term outcome of response to antipsychotics. The results were as follows ; 1) Among total 11 outcome predict factors, only three factors，social-personal adjustement(p〈 0.05), depression(p<0.05), and duration from onset to first admission(p<0.01), were different between two groups. 2) There was no significant difference in short term treatment responses between two groups. 3) Among four symptomatic prognostic factors, which are depression, guilt, emotional blunting and Schneiderian first-rank symptoms, Schneiderian first-rank symptom was related to BPRS score on admission only, but emotional blunting was related to BPRS score during all periods of assessment. These findings suggest that the prognostic value of Schneiderian first-rank symptoms is not so notable in both long term and short term outcome. Rather emotional blunting is significantly correlated with short term treatment response