정신분열병과 한냉응집역가의 관계에 대한 연구

A Study of Cold Agglutinin Titer in Schizophrenia

The purpose of this study was to compare titers o f cold agglutinins in schizophrenic patients with those in normal healthy subjects. 67 schizophrenic patients and 61 healthy control subjects were included in the study. Of 67 schizophrenic patients, 44 patients had been treated with antipsychotic drugs for at least 6 months before the testing, and 21 patients had been drug free for at least 1 year before the testing. The results of the study were as follows : 1) More schizophrenic patients showed significant positive test results than control subjects did. There was a ststistically significant difference between schizophrenic patients and control subjects in positive cold agglutinin testCp^.OOl). 2) There was a statistically significant difference in positive test results between drug treated group and drug free group(p<.00l). 3) The titer of the schizophrenic patients who had positive cold agglutinin tests showed relatively high frequency at above 1: 4，but the titer of the control subjects who had positive cold agglutinin tests showed relatively high frequency at 1: 2. 4) There was no significant difference in sex between subjects with positive cold agglutinin test results and those with negative results(p〉.05). In conclusion, the findings suggest that positive cold agglutinin titers are significantly associ ated with schizophrenia.