§ Hand-Schueller-Christian disease 의 症例

The author has observed 11 year old male patient with Hand-Schuller-Ghristian disease for the past 5 years. The onset was at age of 5 years. This disese is charcterized by classical triad of exophalmos, defects in membranous bone of skull and diabetes insipidus. Following Roentgen therapy, the patient appeared slightghly improved, but the above signs have been persisted with marked growth disturbance and slight behavior disorder. The etiology of this disease is unknown, though many authors had believed this was caused from lipid accumulation as state of cholesterol and its ester. The present tendency is to regard this disease as being closely related to Letterer-Siwe disease and to eosinophilic granuloma