뇌졸중후우울증의 발병기전 : 생물-심리-사회적 통합 모형

Pathogenesis of Post-Stroke Depression : A Bio-Psycho-Social Integrative Model

Depression is common after a stroke and has adverse effects on both the course and prognosis. A proper understanding on the pathogenetic mechanisms of post-stroke depression (PSD) is the first step in the treatment of PSD. PSD should not be considered a purely organic neurological mood syndrome but rather the consequence of a complex interaction model of biological, psychological, and social factors. Based on the pathogenesis, a bio-psycho-social approach is mandatory in the treatment of PSD. A medical team with an integrative bio-psycho-social view should take a pivotal role in the management of PSD.