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KCI등재 학술저널

올란자핀-발프로에이트 병용 치료 시 발생한 가역적 호중구 감소증 2예

Two Cases of Reversible Neutropenia Associated with Olanzapine-Valproate Combination Treatment

  • 4

The novel antipsychotic, olanzapine, has structural and pharmacological properties similar to clozaine. Antipsychotic drugs, as well as mood stabilizers, can cause neutropenia, which can progress to life-threatening agranulocytosis if the medication is not discontinued. We report two cases of reversible neutropenia associated with a olanzapine-valproate combination treatment. This report suggests that patients treated with the combination of olanzapine and valproate should be monitored for the occurrence of leukopenia and neutropenia

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