Objectives：In view of the facts that education about diseases and realization of the need for drugs can improve compliance of the patients, we assessed the knowledge about drugs and medication compliance in psychiatric outpatients. In addition, we investigated factors that influence patients’ compliance to develop a model of medication compliance. Methods：Onehundred twelve male and eighty female psychiatric outpatient were asked about drug information using questionnaires. We developed a model that predicts medication compliance using chi square tests and multiple regression analysis. Results：More than a half of the patients knew at least one of the names and the effects of the drugs they had taken, but many of them didn’t know the side effects of drugs. About eighty percent of the patients showed good compliance. Knowledge of side effects, belief in the benefits of drugs, and level of education could predict medication compliance reliably. Conclusions：Because education level could not be managed by physician, we could enhance compliance through education about drug side effects and benefits of medications.
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