齒科移植을 위한 Dense Calcium Phosphate Ceramics 제재의 物理的성질 및 生物學的 安全性에 관한 研究

The calcium phosphate ceramics are bioactive materials for dental implant that resembles those of dental enamel, dentin and bone, which forming tight bond resembles ankylosis with surrounding bone and soft tissue. Dense calcium phosphate ceramics were made of commercially available tricalcium phosphate salts by compression and subsequent sintering at each temperature 1000ᄋC，1100ᄋ C and 1200°C. Subsequently artificial teeth were made of cylindrical form that consist of a vitallium rod for post & core and a surface o f sintered dense calcium phosphate ceramics for interfacing with alveolar bone. In this experimental study, mechanical and physical properties of sintered calcium phosphate ceramics were obtained from measurement of bulk density, relative density, apparent porosity, compressive strength, modulus of rupture strength, vickers hardness, average pore and grain size. The biological safety of these materials was tested from the tissue culture method using He La Cells. The results of this study were obtained as follows; 1. Tricalcium phosphate ceramics sintered at temperature 1200ᄋC exhibited better mechanical strengths. 2. As much as sintering temperature arised，apparent porosity was reduced, but avarage pore size was larged. 3. The relative density of tricalcium phosphate ceramics sintered at 1200ᄋC was 96.65%. 4. When tricalcium phosphate salts sintered at temperature between 1000°C and 1200°C, they were transformed to (3- Whitlockite. 5. Tricalcium phosphate ceramics exhibited biological safety regardless of sintering temperature.