犬下顆骨에 移植된 TITANIUM 大工齒牙의 周圍組織反應에 關한 病理組織學的 研究 가톨릭 醫科大學 齒科學教室

A HISTOPATHOLOGICAL STUDY ON THE TISSUE REACTION TO THE ENDOSTEAL TITANIUM IMPLANTS IN THE MANDIBLES OF DOGS

The authors observed the histopathological tissue reaction to the Free Design Blade-vent Implants made of pure titanium in the mandibles of dogs. The mandibular left 2nd, 3rd premolar teeth in 4 healthy dogs (4045kg B.W.) were removed. Twelve weeks after the extraction, the F.D.B.I. were implanted into the extracted premolar areas.S ix months after the implantation, the tissue blocks containing the implants were removed. These block sections were fixed in 10% neutral buffered formalin for 2 days and decalcified in 5% trichloracetic acid. The buccal side of the blocks were removed with a knife and F.D.B.I. were detached to buccal from the tissue blocks • Then the implants were prepared and examined in scanning electron microscope. The tissue blocks were embedded by paraffin embedding method and then sectioned by 7m. They were stained with hematoxylin and eosin. The obtained results were as follows: 1. The rete pegs of the epithelium around the sulcus were increased and the inflammatory calls were infiltrated in the connective tissue beneath the sulcular epithelium. 2. There was no fibrous capsule between the titanium and the bone. 3. Compact bone and spongy bone were formed around the titanium. Haversian system, new bone formation by osteoblast, and bone resorption by the osteoclast were observed in the bone. There was no osseous abnormality. 4. On the scanning electron microscope observation, epithelial cells were attached on the neck of titanium implants, that is, mechanical stress results in tearing within epithelium (or periimplant cervical tissue), rather than in a clean separation of the epithelium from implant surface. 5. From this study, it is concluded that force of epithelial attachment of titanium implants is almost equal to the natural teeth and that titanium implant is biocompatible with the living tissue.