방사선 조사가 임프란트 골유착에 미치는 영향에 대한실험 연구

The purpose of this study was to evaluate tissue reaction to X-ray irradiation around implant fixtures used in dental clinic. The thread type of the pure titanium fixture and the titanium plasma spray fixture with 3.8mm in diameter, 8mm in length in Steri-Oss system was chosen. Implants were placed in femoral bone of the dog and irradiated with single 15Gy dose on the 10th postoperative day. Tissue reaction arround the implants was examined with the digital imaging analysis, the mobility test with periotest and the histological examination at 4，8, 16 weeks after implantation. The obtained results were as follows: 1. Under the examination of the light microscopy and Laser confocal microscopy, the maturity of the surrounding bone tissue aruond the implant fixture was formed rapidly with the lapse of time at the non-irradiated group, but the maturity of bone formation was delayed, the amount of new bone formed was less, and specially even at the remodeling stage the surrounding bone tissue around the implant fixture was damaged severely at the irradiated group. 2. Under the examination of the light microscopy and Laser confocal microscopy, the reaction of the bone tissue around the titanium plasma spray implant fixture compared with the pure titanium implant fixture was more activated, and more showed by the maturity of bone formation at both the irradiated group and the non-irradiated group. , 3. As a result of the mobility test with the periotest, the mobility of the implant fixture was reduced without respect to the irradiation, but the reduction width of the mobility of the rradiated group was less compared with the nonirradiated group, that is, the irradiation was the result of the harmful effect to the surrounding bone tissue around the implant fixture. 4. There was no specific differences of the mobility between the titanium plasma spray implant fixture and the pure titanium implant fixture, but the mobility of the titanium plasma spray implant fixture was less compared with the pure titanium implant fixture, that is, the implant fixture of the rough surface with the wide contact to the surrounding bone provided the good stability to the implant..