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자발성(自發性) 고혈압백서(高血壓白鼠)에서 고추(Capsici fructus)의 장기투여(長期投與)가 혈액상(血液像) 및 혈압(血壓)에 미치는 영향(影響)

Effects of Capsici fructus on Blood Figures and Blood Pressure in Spontaneously Hypertensive Rats

The present study was undertaken to investigate effect of feeding hot pepper on the blood pressure and blood figures in SHR. Also studied were effect of hot pepper on plasma electrolyte concentration as well as blood sugar level. Twentytwo SHR at age of 15 weeks were divided into control and CF administered group. And in experimental group hot pepper (1 gm/kg/day) was administered into stomach of each animal by gastric intubation for 8 weeks. The results obtained are as follows: 1) On a day before starting experiment blood pressure(systolic) of the control and CF group were respectively 196.7±4.7 mmHg and 197.4±3.9 mmHg while it changed to 207.4±4.8 mmHg and 227.5±4.2 mmHg respectively on the last day of experiment. Comparing blood pressures of two groups a significant, though not remarkable, difference was observed. 2) No significant differences in blood figures(RBC, WBC, Hct, and Hb level), concentration of plasma electrolytes(Na<sup>+</sup> and K<sup>+</sup>)and blood sugar level were found between control and experimental group.

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