유황오리 추출물의 각종 암세포에 대한 생육억제 효과

This study was carried out to investigate the anticancer effect of extacts from sulfur fed duck carcass. Growth inhibition of cancer cell lines was measured by MTT assay. Eleven cancer cell lines, such as Calu-3(human lung carcinoma), SK-MES-1(human lung carcinoma), HL60(human leukemia), KB(human eprdermoid of mouth carcinoma), Farrow(human melanoma), HEP-2(human larynx carcinoma), SNU-1(human stomach carcinoma), K-562 (human leukemia), WiDr(human colom carcinoma), P388(mouse leukemia) and 3LL(mouse lung carcinoma) showed the growth inhibition higher than 50%, but those, such as SF-188(human brain carcinoma), A-549(human lung carcinoma) and HEC-1B(human uterus carinoma) showed the growth inhibition lower than 50% in the extract of sultur fed duck carcass at the concentraion of 10 ㎎/mL. The sulfur fed duck carcass extract had better growth inhibition than the normal counterpart aginst various cancer cell lines at the concentraion of 10 ㎎/mL. When the effect of growth inhibition of an effluent by different concentrations of methyl alcohol(25, 50, 75 and 100%) tested on Diaion HP-20 column chromatography, an effluent by concentration of 100% methyl alcohol showed the most strong effect of growth inhibition against HEP-2(human larynx carcinoma).