Adhesive Properties of Lactobacillus brevis FSB-1 In Vivo

This study was conducted to evaluate the in vivo gastrointestinal survival and adhesive properties of orally administered Lactobacillus brevis FSB-1. ELISA conducted using polyclonal antibodies specific for L. brevis FSB-1 was able to detect the organism in feces; therefore, we used ELISA to determine the concentration of lactic acid bacteria in feces collected from Wister rats that had been administered 1010 cells/rat/d orally for 20 d. The mean recovery of L. brevis FSB-1 was approximately 107.22 cells/g of wet feces during the oral administration period, and 107.50 and 107.46 at 8 and 10 d after the end of oral administration, respectively. These results indicate that L. brevis FSB-1 was able to survive in the gastrointestinal tract of rats, and that it had a high adhesive property in rat colons.