
Role of peripheral vestibular receptors in the control of blood pressure following hypotension
- Guang-Shi Jin Xiang-Lan Li Yuan-Zhe Jin Min Sun Kim Byung Rim Park
- 대한생리학회-대한약리학회
- The Korean Journal of Physiology & Pharmacology
- 제22권 제4호
- 등재여부 : KCI등재
- 2018.07
- 363 - 368 (6 pages)
Hypotension is one of the potential causes of dizziness. In this review, we summarize the studies published in recent years about the electrophysiological and pharmacological mechanisms of hypotension-induced dizziness and the role of the vestibular system in the control of blood pressure in response to hypotension. It is postulated that ischemic excitation of the peripheral vestibular hair cells as a result of a reduction in blood flow to the inner ear following hypotension leads to excitation of the central vestibular nuclei, which in turn may produce dizziness after hypotension. In addition, excitation of the vestibular nuclei following hypotension elicits the vestibulosympathetic reflex, and the reflex then regulates blood pressure by a dualcontrol(neurogenic and humoral control) mechanism. In fact, recent studies have shown that peripheral vestibular receptors play a role in the control of blood pressure through neural reflex pathways. This review illustrates the dual-control mechanism of peripheral vestibular receptors in the regulation of blood pressure following hypotension.
INTRODUCTION
RESPONSE OF PERIPHERAL VESTIBULAR RECEPTORS FOLLOWING HYPOTENSION
SIGNALING PATHWAY IN THE VESTIBULAR NUCLEI FOLLOWING HYPOTENSION
ROLE OF THE SOLITARY TRACT NUCLEUS(STN) IN HYPOTENSION
ROLE OF THE RVLM IN HYPOTENSION
ROLE OF THE IMC IN HYPOTENSION
ROLE OF THE ADRENAL MEDULLA IN THE VSR
ACKNOWLEDGEMENTS
CONFLICTS OF INTEREST
REFERENCES