창출(蒼朮) Alkaloid 가 Schedule Controlled Behavior 에 미치는 영향(影響)
The Effect of Atractylis Alkaloid on Schedule-Controlled Behavior
- 홍사악(Hong, Sa-Ack) 문동연(Moon, Dong-Yeon)
- 제4권 제1호
- 33 - 36 (4 pages)
The effect on schedule controlled behavior and toxicity of Atractylis alkaloid was investigated in the pigeons which were trained on a multiple fixed-ratio fixed-interval schedule of food presentation. Atractylis alkaloid decreased the rate of responding during both the fixed-interval and fixed ratio component of the schedule at 10 mg/kg. Further depression occurred at 30 mg/kg. This flat dose-response curve for depression of conditioned behavior was typical of tranquilizers. Conclusively it was suspected that Atractylis alkaloid had major tranquilizing activity.