2, 2 Methylene bis (3,4,6 trichlorophenoxy Acetic Acid) 및 Sodium Cholate의 간흡충(肝吸䖝) 산소소비(酸素消費) 및 살충작용(殺䖝作用)

Effects of 2, 2 -Methylene bis-(3,4,6-Trichlorophenoxy Acetic acid) MTPA and Hexachlorophene with or without Sodium Cholate on the Oxygen Consumption in Clonorchis Sinensis

The inhibitory action of oxygen consumption and parasiticidal action of hexachlorophene or MTPA combined with or without sodium cholate in Clonorchis sinensis (C.S) have been observed. The results were obtained as follows. 1. In low concentration of MTPA or Hexachlorophene, they inhibited the oxygen consumption of C.S and in high concentration, inhibition of oxygen consumption and parasiticidal action was more remarkable. 2. The oxygen consumption was inhibited also in the concentration of 10^-2 and 2 X 10^-3g/ml of sodium cholate. 3. In the presence of sodium cholate, oxygen consumption of C.S was more remarkably inhibited by MTPA or Hexachlorophene than the absence of sodium cholate. 4. From those results, it may be considered that sodium cholate combined with MTPA or Hexachlorophene produced potentiation in its action.