Efficiency of<I> Matricaria chamomilla </I>CH<SUB>12</SUB> and number of doses of rabies vaccine on the humoral immune response in cattle

Efficiency of<I> Matricaria chamomilla </I>CH<SUB>12</SUB> and number of doses of rabies vaccine on the humoral immune response in cattle

This study evaluated the effect of <I>Matricaria chamomilla</I> and vaccination frequency on cattle immunization against rabies. Four groups (n = 15 /group) were treated with or without <I>Matricaria chamomilla</I> CH<SUB>12</SUB> and vaccinated with one or two doses of rabies vaccine (30 day interval). No effect of chamomile was found on cattle immunization against rabies; however, antibody titers were protective in cattle vaccinated twice, while 93.3% of cattle vaccinated only once had titers under 0.5 UI/ml after 60 days. In conclusion, the use of chamomile did not alter the humoral immune response in cattle, and two vaccine doses are suggested for achieving protective antibody titers.