Factors affecting the success of resynchronization protocols with or without progesterone supplementation in dairy cows

Factors affecting the success of resynchronization protocols with or without progesterone supplementation in dairy cows

The objective of this study was to investigate factors that influence the success of resynchronization protocols for bovines with and without&amp;nbsp;progesterone supplementation. Cow synchronized and not found pregnant were randomly assigned to two resynchronization protocols:&amp;nbsp;ovsynch without progesterone (P4) supplementation (n = 66) or with exogenous P4 administered from Days 0 to 7 (n = 67). Progesterone&amp;nbsp;levels were measured on Days 0 and 7 of these protocols as well as 4 and 5 days post-insemination. Progesterone supplementation raised the&amp;nbsp;P4 levels on Day 7 (<i>p</i> ＜ 0.05), but had no overall effect on resynchronization rates (RRs) or pregnancy per artificial insemination (P/AI).&amp;nbsp;However, cows with Body Condition Score (BCS) ＞ 3.5 had increased P/AI values while cows with BCS ＜ 2.75 had decreased P/AI rates&amp;nbsp;after P4 supplementation. Primiparous cows had higher P4 values on Day 7 than pluriparous animals (<i>p</i> = 0.04) and tended to have higher&amp;nbsp;RRs (<i>p</i> = 0.06). Results of this study indicate that progesterone supplementation in resynchronization protocols has minimal effects on&amp;nbsp;outcomes. Parity had an effect on the levels of circulating progesterone at initiation of the protocol, which in turn influenced the RR.