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KCI등재
학술저널
Application of vincristine-loaded platelet therapy in three dogs with refractory immune-mediated thrombocytopenia
Application of vincristine-loaded platelet therapy in three dogs with refractory immune-mediated thrombocytopenia
- Hyung-Jin Park, Ja-Won Kim, Kun-Ho Song, Kyoung-Won Seo
- 대한수의학회
- Journal of Veterinary Science
- 제16권 제1호
- 등재여부 : KCI등재
- 2015.03
- 127 - 130 (4 pages)
Three dogs presented with refractory immune-mediated thrombocytopenia (IMT). All patients failed to respond to prednisone, which is<br> considered a mainstay of immunosuppressive therapy. Vincristine-loaded platelets (VLPs), which act selectively on mononuclear&nbsp;phagocytes,were introduced. After the VLPs were transfused, two dogs responded quickly withimproved clinical signs while the third dogwith&nbsp;recurrent IMT was euthanized due to its deteriorating condition. This case report describesthe efficacy of VLP therapy in refractory IMT&nbsp;patients.