Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial
Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial
- Yun-Hsia Hsiao, Charles Chen, Ton Willemse
- 대한수의학회
- Journal of Veterinary Science
- 제17권 제4호
- 등재여부 : KCI등재
- 2016.12
- 549 - 553 (5 pages)
This study was conducted to evaluate the effects of cetirizine in dogs with atopic dermatitis (AD) while fulfilling Favrot’s diagnostic clinical criteria. Dogs received either 3 mg/kg cetirizine (n = 27), or a placebo (n = 23) orally once daily for 14 days in a randomized, double blind, placebo-controlled study, without concomitant medication. The effects were evaluated using a pruritus visual analog scale at the start (day 0) and at day 14. After 14 days, cetirizine clearly had no effect on the pruritus in dogs with chronic AD, and there was no significant difference between groups. These findings indicated that cetirizine (and likely H1 histamine receptor antagonists in general) should not be recommended for the control of pruritus in dogs with long term allergies.