교정장치로부터의 니켈과 크롬의 유리에 관한 연구

A study on the release of nickel and chromium from simulated orthodontic appliances

니켈과 크롬은 대부분의 교정장치를 제작하는데 사용되는 함금을 구성하는 주요한 금속이다. 그러나 이들 금속은 과민반을, 피부염, 천식 들의 주요한 원인이 되며, 이들 금속의 우발적인 픕입에 의해 암이 유발될 수 있음이 보고된바 있다. 이에 하악 standard edgewise 브라켓을 이용한 사분악이 교정장치를 37°C, 0.05% NaCI 용액에 저장하여 교정장치의 부식에 의해 유리된 니켈과 크롬을 Inductively Coupled Plasma(ICP) spectroanalyzer를 이용하여 측정하였다. 니켈 유리량은 제품에 따라 유의한 차이를 가져왔다. Galvanic 조건이나 Sand blasting 처리는 니켈 유리량에 증가를 가져왔으나 통계학적으로 유의하지 않았다.

Nickel and chromium are two major metals used in the alloys of most orthodontic appliances. But these metals. are known to cause hypersensitivity, dermatitis, and asthma. In addition, a significant carcinogenic and mutagenic potential has been demonstrated for compounds containing these metals. The purpose of this study was to find out how much nickel and chromium was released from orthodontic appliances, and which factors would influence the release. The simulated orthodontic appliances were constructed for a half of a mandibular arch and incubated in 0.05% NaCl solution at 37°C. Nickel and chromium release was quantified with an Inductively Coupled Plasma (ICP) spectroanalyzer. The results were as follows : 1. From simulated orthodontic appliances, nickel was released 9.83-70.0µg/day but the release of chromium was not detectable in limit of 10ppb. 2. The amount of nickel release was significantly different between the types of appliances. 3. The galvanic condition increased the amount of nickel release, which was not statistically significant. 4. The. sand blasting increased the amount of nickel release, which was also riot statistically significant.