Purpose: The purpose of this study was to identify relationship between nursing professionalism, nurse image and self-leadership among nursing students. Methods: This research was cross sectional survey design. Participants were 214 nursing students and recruited from 3 or 4-grade nursing students from two university in B metropolitan. Data was collected by structured questionnaire. Data were analyzed using descriptive, t-test, ANOVA, Pearson correlation coefficient, and stepwise regression analysis with SPSS/WIN 24.0 program. Results: First, The average score of the participants nursing professionalism was 3.71±0.496 out of 5, nurse image was 5.55±0.749 out of 7 and self-leadership was 3.85± 0.487 out of 5. Second, As result of analyzing general aspects of the nursing professionalism, statistically significant differences were found in age (F=7.929, p<.001), grade (t=4.616, p<.001), satisfaction of major (F=4.134, p<.01), satisfaction of clinical practices (F=9.431, p<.001), one s own efforts in class (F=3.942, p<.05), adapt to college life (F=4.725, p<.05), one s own health status (F=4.843, p<.01). Third, as result of analysis of correlations between nursing professionalism and nurse image (r=.417, p<.001), nursing professionalism and self-leadership (r=.502, p<.001) and nurse image and self-leadership (r=.380, p<.001) of the nursing students were statistically significant relationships. Forth, Factors significantly affecting nursing professionalism were self-leadership (β=.401, p <.001) and nurse image (β=.265, p<.001). Explanatory power of the model was 30.5%. Conclusion: It is necessary to develop a program for continuous teaching and education that will help self-leadership and nurse image.
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