Paraneoplastic Neutrophilia Originating from an Anaplastic Transformation of Papillary Thyroid Carcinoma in a Metastatic Pleural Lesion
Paraneoplastic Neutrophilia Originating from an Anaplastic Transformation of Papillary Thyroid Carcinoma in a Metastatic Pleural Lesion
- 조선대학교 의학연구원
- The Medical Journal of Chosun University
- 제39권 제1호
- 2014.03
- 39 - 42 (4 pages)
Marked neutrophilia associated with neoplasia is a relatively rare finding and has been considered as a paraneoplastic manifestation. Thyroid cancer seldom presents with paraneoplastic leukocytosis. We report on a case of a 69-year-old man who presented with paraneoplastic leukocytosis seven months after undergoing total thyroidectomy and I-131 therapy for treatment of papillary thyroidcarcinoma. We found neither bone marrow involvement of malignant cells nor hematologic malignancy. Based on elevated levels of serum granulocyte colony-stimulating factor, we concluded that the cause was paraneoplastic leukocytosis. Another interesting point was the anaplastic transformation in the pleural metastatic site. It usually occurs in the intrathyroid or regional lymph node.
Introduction
Case report
Discussion