고령의 쇼그렌 증후군 환자에서의 전이성 폐암으로 오인된 림프종

Diffuse Large B-cell Lymphoma Mimicking Metastatic Lung Cancer with Sjögren’s Syndrome

Prognosis of the patients with lung cancer with lung-to-lung metastasis are known to be poor and frequently old aged persons with multiple nodules on imaging study abandon more invasive procedure including bronchoscopy and VATS (Videoassisted thoracoscopic surgery) to get tissue confirmation. Sjogren’s syndrome (SS) associated lung lesion mimicking lung cancer has a chance to have more favorable diseases including lymphoma. A 78-year-old woman with SS was admitted due to slowly progressive exertional dyspnea and multiple nodules on imaging study. She and her family gave up invasive diagnostic procedures at first due to old age but short term rapid change of dyspnea and nodules on chest CT brought out invasive procedures and diffuse large B-cell lymphoma was diagnosed. Dyspnea and nodules on imaging were improved after R-CHOP chemotherapy.