급성 호흡기 바이러스 감염이 가와사키병에 미치는 영향에 관한 연구

Influence of Acute Respiratory Virus Infection on Kawasaki Disease

The aim of this study was to determine the effect of acute respiratory viral infection on Kawasaki disease. From July 2016 to June 2018, among the patients who underwent respiratory virus screening at the Kwangju Christian Hospital, those diagnosed 88 patients with Kawasaki disease were enrolled in this study. The effects of acute respiratory viral infection on Kawasaki disease were compared according to whether 2^nd intravenous immunoglobulin (IVIG) treatment was administered or not, and whether coronary artery complications occurred. Respiratory virus was detected in 44 out of 88 patients. 2^nd IVIG treatment rates were 16% (n=7) and 27% (n=12) in the virus positive group and the virus negative group, respectively (p>0.05). The incidence of coronary artery complications was 11% (n=5) and 25% (n=11) in the virus positive group and the virus negative group, respectively (p>0.05). There was no statistically significant correlation between the 2^nd IVIG administration and coronary artery complications following the detection of respiratory virus in patients with Kawasaki disease. We think it is necessary to actively study the effects of acute respiratory viral infection on Kawasaki disease through largescale studies of multiple centers in the future.