방사선치료 종료시기 암환자의 영양상태, 식욕상태 및 삶의 질에 관한 조사연구

A Study on the Nutritional Status, Appetite Status, and Quality of Life of Cancer Patients Completing Radiotherapy

This study was conducted to identify nutritional status, appetite status, and the score of quality of life of 42 cancer patients who completed executive cycles of radiotherapy on chest or pelvic area. The data were gathered from April 1 to December 30, 1996 through questionnaires of anorexia, quality of life and the anthropometric and biochemical measures such as weight, triceps skinfold thickness, mid-arm circumference, mid-arm muscle circumference, albumin, total Iymphocyte count, and hemoglobin. The data were analyzed by t-test, ANOVA, two-way ANOVA, and multiple regression analysis. The results were summarized as follows : 1. There were no significant differences in all nutritional status by age. 2. As for the anthropometric measures, significant differences were found by gender in TSF, MAC, & handgrip(t =-7.41, p =.0000; t =-2.56, p =.0142; t =6.38, p =.0000); TSF and MAC were higher in female than in male, and the reverse was handgrip. As for the biochemical measures, significant differences were found by gender in hemoglobin & total lymphocyte count((t =4.46, p =.0001; t =2.26, p =.0295). Hemoglobin and total Iymphocyte count in male were higher than those in female. 3. As for the anthropometric and biochemical measures, significant differences were found by cancer site in TSF, MAC, handgrip, albumin, and hemoglobin(t =-4.26, p =.0001; t =-3.33, p =.0019; t =3.73, p =.0006; t =-2.42, p =.0204; t =2.39, p =.0216). TSF, MAC, & albumin level in pelvic area were higher than those in chest area, handgrip and hemoglobin in chest area were higher than those in pelvic area. 4. Total lymphocyte count differed significantly by total radiation dosage(t =-2.15, p =.0373); TLC of patients receiving over 6,000 rads was higher than that of patients receiving under 6,000 rads. 5. Appetite score differed significantly by types of treatment and total radiation dosage(t =3.11 , p =.0036; t =-2.53, p =.0155); appetite score was higher in patients receiving irradiation only than in patients receiving operation & irradiation and was higher in patients receiving over 6,000 rads than under 6,000 rads. 6. The relationships of nutritional status, appetite status, and quality of life were as follows. Significant correaltions were observed between body weight， MAC, MAMC, & hemoglobin(r =.69, p =.0001; r =.68, p =.0001; r =.53, p=.0003); TSF was significantly related with MAC, handgrip, hemoglobin(r =.58, p =.0001; r =-.65, p =.0001; r =-.32, p =.04); MAC was significantly related with MAMC(r =.78, p =.0001); MAMC with hemoglobin(r =.47, p =.0017); handgrip with hemoglobin & TLC(r =.34, p =.0271; r =.30, p =.0559); and hemoglobin with TLC(r =.42, p =.0063). 7. There were no significant relation with appetite score by variables of the nutritional status. Significant correlation was observed between quality of life and appetite score(r =-.49, p =.0014). Predictor which explained score of quality of life was only appetite status. which was 24.43%(,9 =-.7559. F=11.96. p=.0014).