흉부와 골반부 방사선치료를 받은 암환자 영양상태평가

Assessment of Nutritional Status in Chest and Pelvic Cancer Patients undergoing Radiation Therapy

This study was conducted to assess nutritional status of 48 cancer patients who completed executive cycles of radiation therapy on chest or pelvic area. The data were gathered May 1 to December 30, 1996 through the anthropometric and biochemical measures such as weight, triceps skinfold thickness, mid-arm circumference, mid-arm muscle circumference, hand grip, serum albumin, hemoglobin, & total Iymphocyte count. The data were analyzed by percentage, Mean±SD, chi-square test, t-test, Pearson s correlation & two-away ANOVA using SAS program. The results were summarized as follows : 1. Eighty five percentage of the subjects were the fifties to sixties. Cancers of the chest area occur in all men(excluding one), 56% among all subjects. The others occur in pelvic area and 71 % among them were women. The number of patients who received curative radiation therapy only were 58% and the others had operation and adjuvant radiotherapy. Patients who irradiated less than 6,000rads were 54% and the others had radiation dose above 6,000rads. 2. TSF was 8.75±4.10mm in men and 14.97 ± 5.44mm in women. These come under 5th~50th% among normal persons. Total Iymphocyte count of chest cases was less than 900/㎥, ie, moderate depletion and that of pelvic cases was less than 800/㎥ ,ie, severe depletion. 3. There were significant differences of TSF, MAC, level of hemoglobin, level of albumin, & hand grip by cancer areas. But there were no significant differences of the body weight, MAMC, & TLC by cancer areas. TSF, MAC, & levels of serum albumin on pelvic cases were higher than those on chest cases(t=4.26, p=.000; t=3.33, p=.002; t=2.42, p=.020). Hand grip and level of hemoglobin on pelvic cases were lower than those on chest cases(t=3.73, p=.000; t=2.39, p=.021). 4. In completing radiation therapy, body weight was positively correlated with MAC, MAMC, level of hemoglobin, & TLC(r =.667, p =.0001; r =.677, p =.0001; r =.529, p =.0001; r =.353, p =.014). TSF was positively correlated with MAC(r=.551 , p =.0001), negatively with level of hemoglobin & handgrip(r=-.312, p=.030; r =-.650, p =.0001). MAC was positively correlated with MAMC(r =.827, p =.0001). Level of hemoglobin was positively correlated with body weight, MAC, MAMC, TLC & handgrip(r =.529, p =.0001; r =.388, p =.006; r =.413, p =.003; r =341 , p =.021).