실험적으로 유발된 궤양성 대장염의 동물 모델

Animal Models of Ulcerative Colitis

Inflammatory bowel disease (IBD) is an idiopathic disease of the alimentary tract including small and large intestine. Ulcerative colitis (UC) is one of the IBD, and its typical features are mucosal inflammation and loss of barrier function. Although the mechanisms for IBD induction and progression are not completely understood, studies using animal models of UC have a good benefit to understand the clue of inflammation-associated colorectal carcinogenesis. It is important to choose suitable animal model according to various project.