고실성형술에서 Propofol-Remifentanil을 이용한 전정맥마취와 Sevoflurane을 이용한 흡입마취의 비교

Comparison of Total Intravenous Anesthesia using Propofol-Remifentanil and Inhalation Anesthesia using Sevoflurane for Tympanoplasty

Background: Total intravenous anesthesia (TFVA) using propofol and remifentanil was compared with inhalation anesthesia using sevoflurane in patients undergoing tympanoplasty. The aim of the present study was to compare hemodynamic changes during induction and maintenance of anesthesia as well as the rates of induction and recovery following each anesthetic technique. Methods: Thirty patients (ASA physical status 1，2) scheduled for elective surgery were divided randomly into 2 groups. Group I (propofol-remifentanil) was induced and maintained with propofol 3.0 |i.g/ml and remifentanil 0.2 |i g/kg/min. Group II (sevoflurane) was induced with thiopental sodium 5 mg/kg and maintained with 2.0 vol% sevoflurane. The patient’s blood pressure and heart rate were measured before and after tracheal intubation, skin incision, and every 30 minutes interval. The patient s ability to recovery of the spontaneous breathing, and open their eyes and respond to simple verbal commands was assessed at 15 to 30 seconds intervals after discontinuation of the anesthetics. Results: The systolic and diastolic blood pressure and heart rate after intubation were increased in groups II, and were unchanged in groups I as compared to preintubation values. Emergence times were significantly shorter in group I than group II. Conclusion: We concluded that TIVA using propofol and remifentanil can provide hemodynamic changes and rapid emergence than inhalation anesthesia using sevoflurane.