인슐린 자가면역 증후군 2 예

Two Cases of Insulin Autoimmune Syndrome

Autoimmune hypoglycemia is one of the rare causes of hypoglycemia, and characterized by hyperinsulinemia. Insulin autoimmune syndrome is characterized by insulin autoantibody, hyperinsulinemia, and fasting hypoglycemia without previous insulin immunization. Insulin autoimmune syndrome is usually related to autoimmune disease such as Graves’ disease and to previous exposure to drugs. This syndrome is a self-limited disorder. The hypoglycemia was treated with prednisolone and the patient recovered from this. Recently we experinenced two cases of insulin autoimmune syndrome that developed symptomatic hypoglycemia during both the fasting and oral glucose tolerance test. Here in, We present those cases with a review of the literature.