비타민D 보충 요법이 폐경 후 여성 근력에 미치는 효과: 메타분석

Effect of Vitamin D on Muscular Strength in Postmenopausal Women: A Meta-Analysis

Purpose: Postmenopausal women are a unique population with high risk for the degeneration of muscle. The aim of the present meta-analysis was to accurately evaluate the effects of vitamin D on muscular strength in postmenopausal women. Methods: A review was conducted using electronic databases, including PubMed, EMBASE, Ovid Medline, CINAHL complete, and the Cochrane Library from inception through 19 March 2019. Included studies were selected by two independent reviewers. The meta-analysis were performed using Review Manager 5.3 software. Results: A total of nine randomized controlled clinical trials were included in this review. Vitamin D interventions led to no changes in the upper limb muscle strength (mean difference –0.16, 95% CI: –1.09 to 0.77), lower body muscle strength (standard mean difference 0.08, 95% CI: –0.11 to 0.26), and back/hip muscle strength (standard mean difference 0.06, 95% CI: –0.05 to 0.17). Conclusion: Pooled results from eight studies indicated that supplementation of vitamin D did not increase muscle strength in postmenopausal women. Apparently, the present review suggests that supplementation of vitamin D alone had no didn’t show any beneficial effects on muscle strength in postmenopausal women.