소아청소년에서 보초용종의 임상경과
Clinical progress of sentinel polyp in children and adolescents
- 조선대학교 의학연구원
- The Medical Journal of Chosun University
- 제46권 제2호
- 2021.11
- 47 - 50 (4 pages)
Background: The sentinel polyp (SP) is a term used to refer to inflammatory polyps that are commonly associated with gastroesophageal reflux resulting in esophagitis. However, not only clinical progress, but also relationship of clinical characteristics with clinical outcomes are not well established in children and adolescents. Study Objectives: This study aimed to evaluate the relationship between clinical progress and individual characteristics and the prognosis of SP. Methods: During 8 years from March 2013 through April 2021, 125 patients with symptoms of chronic gastritis or gastroesophageal reflux disease were evaluated and followed with upper gastrointestinal endoscopy and biopsy at least twice. The clinical and laboratory records, macroscopic and microscopic findings of endoscopy were reviewed retrospectively. Results:Eleven cases of SP were identified. Proton pump inhibitors and antacids were prescribed for six months each in 8 cases of SP, and endoscopic follow up was performed after a year in 8 cases. The resolution of SP was detected in 5 (62.5%) cases (improved group). 3 out of 5 cases had a well-controlled diet in the improved group, and 2 out of 3 in the not improved group. Odds ratio was 0.75, and the P-value was 0.85. Conclusions: After 1 year of PPI and antacids medication, SP showed improvement in more than half of the cases (5 out of 8, 62.5%). The association of SP improvement and diet control appeared to be low. A further research is needed on a larger scale.
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